DOI:10.29111/ijlrst ISRA Impact Factor:3.35
Research Paper Open Access
International Journal of Latest Research in Science and Technology Vol.8 Issue 2, pp 8-12,Year 2019
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Received : 01 April 2019; Accepted : 14 April 2019 ; Published : 30 April 2019
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| Article No. | 10969 |
Development of an analytical method to determine Anthraquinones (derivative drugs phenolic compounds) by coupling reaction with diazotized solution of p- amino benzoic acid in the presence of buffer solution Na2HPO4 (pH= 10.8) to gave a compound with a single azo dye salt having orange color soluble in water with high absortivity at a wave length 449 nm , an early study to have a perfect optimum condition was made for the determination. A calibration curve for a range of concentration (6.21x10-4 – 2.21x10-2 μg.mL-1) was taken and the value of molar absortivity was 2.1x104 L.mol-1.cm-1, with a relative standard deviation more than 1.35% and a recovery 97.66%. The described procedure is very simple, low-time-consuming, provides high throughput of examinated samples, and could be used for routine screening and confirmatory analyses as well. The method was successfully validated to the analysis of the (derivative drugs phenolic compounds) in biological samples.
Copyright © 2019 Dr. Ahmed Jassim Muklive AL-ogaidi et al. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Dr. Ahmed Jassim Muklive AL-ogaidi , " Quantity Determination Of Derivative Drugs Phenolic Compounds By Coupling Reaction With P- Amino Benzoic Acid ", International Journal of Latest Research in Science and Technology . Vol. 8, Issue 2, pp 8-12 , 2019
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