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International Journal of Latest Research in Science and Technology

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IN VITRO NEW BIOPOLYMER FOR BONE GRAFTING AND BONE CEMENT

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International Journal of Latest Research in Science and Technology Vol.4 Issue 2, pp 46-55,Year 2015

IN VITRO NEW BIOPOLYMER FOR BONE GRAFTING AND BONE CEMENT

Gehan A. Raouf,Hana Gashlan, Alaa Khedr, Salem Hamedy, Hind Al-jabbri

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Received : 05 April 2015; Accepted : 08 April 2015 ; Published : 30 April 2015

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Article No. 10490
Abstract

Cements based on synthetic calcium sulfate is among the most investigated material for dental and orthopedic applications in reconstructive surgery. To overcome the short-term cytotoxic effect, brittleness and fast resorption of calcium sulfate dihydrate(CSD), as bone substitute material, CSD was doped with Lepidium sativum water extract(LS) powder and mixed with cow bone mineral (BM) (1: 0.04: 1: wt/wt ratio respectively). The Fourier Transform Infrared (FTIR) spectra of BM-CSD, BM-CSD-LS, and BM-LS composites, compared to BM, were recorded. LS was analyzed by using Gas Chromatography/ Mass Spectroscopy(GC/MS) and Scanning Electron Microscope-Energy Disspersive X-ray(SEM-EDX). The results revealed that the total carbonate/phosphate ratio, type B-carbonate substitution, and acid phosphate content increased dramatically in all tested composites, the maximum increase was detected in BM+CSD+LS composite. Other forms, rather than B-carbonate substitution, takes place such as substitution with Zn, Mg and amino acids. The BM-crystallinity (BMC) decreased significantly in both BM+CSD, B+CSD+LS while, it is slightly decreased in BM+LS composite compared to BMC. Thus, addition of CSD to bone mineral leads to decrease in crystallinity while adding LS only or doping CSD with LS increases the crystallinity of bone mineral compared to BM+CSD composite with increasing in the apatite crystal size and the acid phosphate content as well.

Key Words   
Bone Mineral Crystallinity, Bone grafting, Calcium Sulphate Dihydrate, Fourier Transform Infrared

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To cite this article

Gehan A. Raouf,Hana Gashlan, Alaa Khedr, Salem Hamedy, Hind Al-jabbri , " In Vitro New Biopolymer For Bone Grafting And Bone Cement ", International Journal of Latest Research in Science and Technology . Vol. 4, Issue 2, pp 46-55 , 2015

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